Health

Pfizer Vaccine Efficacy, Price, Side Effects, Dosage Difference

 

On December 11, 2020, The COVID-19 vaccine developed by Pfizer-BioNtech was approved for emergency use in anyone aged 16 years and above. It is an mRNA vaccine just like the modern vaccine. In the United States, this was the first COVID-19 pfizer Vaccine approved for emergency use. To know more, read the article.

pfizer vaccine

Pfizer is a vaccination that uses messenger RNA (mRNA). This vaccination causes your body’s cells to generate the coronavirus’s unique spike protein through a genetic code called RNA.
The spike protein then acts as a threat to the cells of your immune system, which begin to mount an immunological response against it. The RNA obtained from vaccination does not affect your DNA and is destroyed by your body.

In two doses, Pfizer’s vaccine stimulates the body to produce the specific spike protein for this virus. This information will be carried by your immune system, which creates an immunological response, including antibodies. There is no live virus in Pfizer and it cannot give you COVID-19.

pfizer vaccine efficacy

Effectiveness measures how effectively vaccination works in a controlled context with a specific population.
Vaccine effectiveness in the real world may be low for a variety of reasons, but this is not a comment on vaccination. In a “real world” scenario, vaccination was to prevent transmission by about 90%, including asymptomatic ones.
Another reason why real-world efficacy may differ from clinical trial results is this. Clinical studies only reveal what is happening to the virus at that particular moment. The frequency of the virus may change when a vaccine is available to the general public, and new variations may exist. This is very specific and expected.

There is currently no vaccination that can completely prevent transmission. So it is still necessary to wash hands, wear masks and practice social distancing.
The Pfizer vaccination takes two doses spaced 21 days apart for it to be fully effective. Despite this, the vaccine has proven to have a high effectiveness rate of up to 85% after a single dose.
Multiple transmissions occur after the first dose before the body produces enough antibodies to prevent infection during the first ten days after vaccination.

PHE re-analyzed research on the effectiveness of the Pfizer vaccine, published in the New England Journal of Medicine. According to the PHE reanalysis, this vaccine showed an effectiveness rate of 89 percent for days 15 to 21 after the first dose and before the second dose on day 21, as shown in Table 1. In this research, the range was 52 percent to 97 percent. ,
By the first week after the second dose, protection from the first dose had increased to 91 percent, with a range of 74 percent to 97 percent.

pfizer vaccine price

According to reports, the price of Pfizer-BioNtech COVID-19 vaccine could be as low as $10 or Rs 730 in India. According to media reports, a source claimed, “It is a single digit price per dose.” “The government’s vaccination program is offered at a non-profit fee.” The price of this vaccine in industrial markets such as the United States, the United Kingdom, and Europe is about half that of Pfizer. The above price could potentially be the world’s lowest for mRNA-based COVID-19 vaccination.
The Pfizer COVID vaccination costs $19.5 (1,423) per dose in the United States and about $21 (Rs 1,532) in the United Kingdom. Pfizer was priced at around $18.9 per dose in the European Union, but price discussions continue for a higher price of $23.2 (Rs 1,693) per dose. As a result, Pfizer’s COVID-19 vaccine in India could be the cheapest in the world.

Pfizer Vaccine Side Effects

Adverse effects of Pfizer can fall into two categories:

common side effects

  • You may have some temporary adverse effects after taking Pfizer, such as any vaccinations. These are signs that your immune system is working properly.
  • Injection site discomfort or swelling, as well as fatigue, are common adverse effects after Pfizer.
  • Headaches can be caused by muscle or joint discomfort.
  • Fever and chills are common symptoms.
  • Most patients have minor symptoms and recover quickly.
  • Men younger than 30 are more likely to die within ten days of receiving a second vaccination dose.

rare side effects

  • In young individuals, myocarditis or pericarditis may occur.
  • Rarely, myocarditis and pericarditis can occur after a Pfizer vaccination.
  • If you notice any of the following symptoms after receiving the Pfizer vaccination, see a doctor or go to the hospital right away:
  • Shortness of breath, chest pain, pressure or discomfort in the chest, irregular heartbeat or palpitations.’
  • In US men there are 10 cases per million after the first dose and 67 cases per million after the second treatment. The TGA is monitoring the population at risk in Australia.
  • The danger for children between the ages of 5 and 11 has not yet been determined. Pfizer’s COVID-19 study did not enroll enough participants to determine the rates of myocarditis and pericarditis. Millions of doses of this vaccine have been administered to children aged 5 to 11 around the world without any specific safety concerns.
  • The benefits of vaccination outweigh the risks of this very uncommon complication, and vaccination should continue for all eligible age groups.

dosage difference

The Pfizer vaccine requires two doses, given three to six weeks apart, for 12 and older. Unless directed by a medical expert, children ages 5 to 11 require two doses of Pfizer for Children (one-third of the adult dose), given eight weeks apart. Everyone 16 years of age and older who received an initial course of COVID-19 vaccination at least three months ago is eligible for a booster dose. After your second dose or booster, you may not be completely protected from COVID-19 for 7 to 14 days.

Conclusion

For example, the COVID-19 vaccines from Pfizer-BioNtech and Moderna, require two doses. For example, the Johnson & Johnson vaccination requires an injection. Because the immunological response to the first dose is very poor, some vaccinations require two doses. The second dose helps to strengthen this immunological response. Keep your COVID-19 vaccination record card once you have been vaccinated. This can help you remember which vaccine you were given and when to get your second dose.

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